Figure 5. Effect of LTD₄ on IP1 production for the wild type and 5 mutants of the human CysLT1 receptor.

IP1 production following stimulation of the wt and 5 mutants of the hCysLT1 receptor transfected using the protocol detailed in this manuscript and published in Luginina (2019). Results were normalized to the wt receptor as described and represent the mean % IP1 production ± SEM of three independent experiments each done in quadruplicate.