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Fit parameters for peptidase activation of ClpP1P2 by ADEPs and fragments
| compound | Peptidase stimulation | ||
|---|---|---|---|
| EC50 (µM)a | Hill coefficienta | R2 | |
| 1a b | 38 ± 2 | 1.9 ± 0.07 | 0.998 |
| 1b | 6.7 ± 0.2 | 2.1 ± 0.1 | 0.997 |
| 2a b | 46 ± 0.4 | 3.3 ± 0.2 | 0.999 |
| 2b | 67 ± 0.5 | 3.4 ± 0.07 | 0.999 |
| 2c | 16 ± 0.3 | 3.7 ± 0.2 | 0.998 |
| 2d | 58 ± 2 | 3.5 ± 0.3 | 0.998 |
| 2e | 35 ± 0.3 | 3.2 ± 0.07 | 0.999 |
| 3 b | 94 ± 4 | 2.7 ± 0.1 | 0.998 |
fit value ± standard error
average of three biological replicates
