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. 2021 Jan 28;16(1):e0245670. doi: 10.1371/journal.pone.0245670

Table 1. Baseline characteristics among different smoking and drinking groups by sex.

Nonsmoker/Nondrinker Drinker Smoker Smoker/Drinker P
All participants
Number of subjects 8029 2159 2309 4583
Age (years) 50.30 (10.06) 59.26 (9.83) 60.89 (10.03) 59.57 (9.37) <0.001
Age group <0.001
<50 1798 (22.39) 483 (22.37) 395 (17.11) 868 (18.94)
50–59 2885 (35.93) 754 (34.92) 795 (34.43) 1714 (37.40)
60–69 2077 (25.87) 599 (27.74) 636 (27.54) 1321 (28.82)
70–79 954 (11.88) 247 (11.44) 392 (16.98) 555 (12.11)
≥80 315 (3.92) 76 (3.52) 91 (3.94) 125 (2.73)
Middle school education (%) 2109 (26.32) 669 (31.00) 738 (31.99) 1752 (38.28)
Rural (%) 6236 (77.75) 1656 (76.74) 1839 (79.71) 3603 (78.65) 0.064
Married (%) 6838 (85.17) 1896 (87.86) 1966 (85.15) 4152 (90.60) <0.001
Hypertension (%) 3159 (39.34) 834 (38.63) 810 (35.08) 1764 (38.49) 0.003
Dyslipidemia (%) 2630 (32.76) 659 (30.52) 770 (33.35) 1359 (29.65) 0.001
Diabetes (%) 653 (8.13) 178 (8.24) 167 (7.23) 288 (6.28) 0.001
Overweight or obesity (%)* 2886 (46.29) 712 (42.61) 588 (32.15) 1118 (31.98) <0.001
History of CVD (%) 1211 (15.08) 271 (12.55) 333 (14.42) 556 (12.13) <0.001
Male
Number of subjects 1091 1083 1767 4391
Age (years) 61.42 (10.47) 59.20 (9.96) 60.17 (9.75) 59.37 (9.26) <0.001
Age group <0.001
<50 198 (18.15) 253 (23.36) 319 (18.05) 855 (19.47)
50–59 332 (30.43) 367 (33.89) 638 (36.11) 1655 (37.69)
60–69 308 (28.23) 299 (27.61) 490 (27.73) 1254 (28.56)
70–79 202 (18.52) 124 (11.45) 264 (14.94) 517 (11.77)
≥80 51 (4.67) 40 (3.69) 56 (3.17) 110 (2.51)
Middle school education (%) 428 (39.34) 460 (42.51) 668 (37.83) 1724 (39.32) <0.001
Rural (%) 777 (71.22) 772 (71.35) 1390 (78.75) 3441 (78.38) <0.001
Married (%) 978 (89.64) 1003(92.70) 1563(88.46) 4008(91.28) <0.001
Hypertension (%) 402 (36.85) 425 (39.24) 570 (32.26) 1671 (38.06) <0.001
Dyslipidemia (%) 356 (32.63) 333 (30.75) 573 (32.43) 1300 (29.61) 0.077
Diabetes (%) 76 (6.97) 95 (8.77) 116 (6.56) 275 (6.26) 0.031
Overweight or obesity (%)* 300 (38.56) 342 (42.59) 408 (29.76) 1058 (31.63) <0.001
History of CVD (%) 139 (12.74) 143 (13.20) 197 (11.15) 511 (11.64) 0.292
Female
Number of subjects 6938 1076 542 192
Age (years) 58.97 (9.96) 59.32 (9.70) 63.22 (10.56) 64.30 (10.49) <0.001
Age group <0.001
<50 1600 (23.06) 230 (21.38) 76 (14.02) 13 (6.77)
50–59 2553 (36.80) 387 (35.97) 157 (28.97) 59 (30.73)
60–69 1769 (25.50) 300 (27.88) 146 (26.94) 67 (34.90)
70–79 752 (10.84) 123 (11.43) 128 (23.62) 38 (19.79)
≥80 264 (3.81) 36 (3.35) 35 (6.46) 15 (7.81)
Middle school education (%) 1681 (24.27) 209 (19.42) 70 (12.94) 28 (14.58) <0.001
Rural (%) 5459 (78.77) 884 (82.16) 449 (82.84) 162 (84.82) 0.003
Married (%) 5860 (84.46) 893 (82.99) 403 (74.35) 144 (75.00) <0.001
Hypertension (%) 2757 (39.74) 409 (38.01) 240 (44.28) 93 (48.44) 0.008
Dyslipidemia (%) 2274 (32.78) 326 (30.30) 197 (36.35) 59 (30.73) 0.092
Diabetes (%) 577 (8.32) 83 (7.71) 51 (9.41) 13 (6.77) 0.582
Overweight or obesity (%)* 2586 (47.39) 370 (42.63) 180 (39.30) 60 (39.74) <0.001
History of CVD (%) 1072 (15.45) 128 (11.90) 136 (25.09) 45 (23.44) <0.001

*missing N = 2035 for male and N = 1814 for female.