Table 2. Multivariable model with and without clustering in all preterm infants.
Un-clustered | Clustered on familial relation | |||||
---|---|---|---|---|---|---|
Variable | Parameter estimate(s) | SE | P-value | Parameter estimate(s) | SE | P-value |
Intercept | 11.02142 | 5.68115 | 0.0525 | 10.60334 | 5.63184 | 0.0598 |
Maternal race | ||||||
Asian | -0.15719 | 0.03980 | <0.0001* | -0.15903 | 0.03946 | <0.0001* |
Black/African American | 0.00283 | 0.02518 | 0.9105 | 0.00383 | 0.02496 | 0.8779 |
Multiple races | -0.09668 | 0.05513 | 0.0796 | -0.09575 | 0.05465 | 0.0799 |
Other | -0.00151 | 0.02850 | 0.9579 | -0.00227 | 0.02826 | 0.9361 |
Unknown | -0.02251 | 0.04450 | 0.6130 | -0.01815 | 0.04412 | 0.6808 |
Maternal first trimester BMI | ||||||
Underweight | -0.10882 | 0.05894 | 0.0650 | -0.11562 | 0.05843 | 0.0479 |
Overweight | 0.01170 | 0.01860 | 0.5294 | 0.00848 | 0.01843 | 0.6456 |
Obese | 0.03154 | 0.01762 | 0.0736 | 0.02956 | 0.01747 | 0.0908 |
Maternal hypertension during pregnancy | -0.00294 | 0.01909 | 0.8777 | -0.00360 | 0.01892 | 0.8492 |
Preeclampsia | 0.00653 | 0.01859 | 0.7256 | 0.00851 | 0.01843 | 0.6444 |
Birth year | -0.00552 | 0.00282 | 0.0507 | -0.00531 | 0.00280 | 0.0578 |
Multiple(s) | 0.02730 | 0.01593 | 0.0867 | 0.03036 | 0.01579 | 0.0547 |
Gestational age (weeks) | 0.01599 | 0.00569 | 0.0049* | 0.01543 | 0.00564 | 0.0062* |
Birth weight (gr) | -0.00002 | 0.00003 | 0.4994 | -0.00002 | 0.00003 | 0.5108 |
Birth length (cm) | -0.00022 | 0.00337 | 0.9469 | 0.00008 | 0.00334 | 0.9802 |
Head circumference (cm) | -0.00915 | 0.00529 | 0.0837 | -0.00894 | 0.00524 | 0.0884 |
TPN | -0.02370 | 0.02119 | 0.2634 | -0.02204 | 0.02100 | 0.2941 |
Received dextrose | 0.03910 | 0.01818 | 0.0316* | 0.03780 | 0.01802 | 0.0361* |
Length of birth hospitalization stay (days) | -0.00029 | 0.00037 | 0.4378 | -0.00029 | 0.00037 | 0.4307 |
Abbreviations: BMI, body mass index; cm, centimeters; gr, grams; SE, standard error; TPN, total parenteral nutrition.
Referent groups: White maternal race, normal maternal first trimester BMI, no hypertension, no preeclampsia, singleton, no TPN, no dextrose.
*p<0.05. P-values were calculated using multivariable linear regression.