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. 2021 Jan 28;16(1):e0245387. doi: 10.1371/journal.pone.0245387

Table 5. Extremely and moderately preterm models with prematurity-associated conditions.

Extremely preterm Moderately preterm
Variable Parameter estimate(s) SE P-value Parameter estimate(s) SE P-value
Intercept 19.65406 18.58351 0.2907 5.16553 5.46977 0.3453
Maternal race
    Asian -0.21821 0.13315 0.1018 -0.06379 0.04363 0.1442
    Black/African American 0.00894 0.06816 0.8957 0.01126 0.02542 0.6578
    Multiple races -0.39875 0.15481 0.0103* -0.05709 0.05676 0.3149
    Other 0.04129 0.09334 0.6584 0.01140 0.02757 0.6794
    Unknown 0.03405 0.12208 0.7804 -0.06567 0.04467 0.1420
Maternal first trimester BMI
    Underweight -0.25808 0.21640 0.2336 -0.06826 0.05664 0.2286
    Overweight 0.00252 0.05995 0.9665 0.01282 0.01687 0.4474
    Obese -0.03903 0.05690 0.4931 0.01522 0.01546 0.3253
Maternal hypertension during pregnancy 0.06032 0.07347 0.4120 -0.02297 0.01573 0.1446
Preeclampsia -0.00084 0.07457 0.9910 0.02373 0.01568 0.1307
Birth year -0.00928 0.00923 0.3152 -0.00256 0.00272 0.3478
Multiple(s) -0.00620 0.05308 0.9070 0.04542 0.01385 0.0011*
Gestational age (weeks) -0.00583 0.02319 0.8017 0.01111 0.00784 0.1572
Birth weight (gr) 0.00022 0.00017 0.1896 -0.00001 0.00003 0.6618
Birth length (cm) -0.01210 0.01081 0.2635 -0.00083 0.00277 0.7645
Head circumference (cm) -0.02160 0.01841 0.2414 -0.00696 0.00407 0.0879
TPN -0.03667 0.18426 0.8423 0.00185 0.02443 0.9397
Received dextrose 0.11587 0.05107 0.0237* 0.01456 0.02384 0.5416
Length of birth hospitalization stay (days) -0.00049 0.00088 0.5749 -0.00031 0.00034 0.3673
BPD 0.04352 0.06179 0.4815 -0.01114 0.02341 0.6343
IVH -0.05261 0.06085 0.3876 0.00217 0.02553 0.9323
NEC 0.08422 0.12069 0.4856 0.03182 0.04968 0.5220
PDA -0.00120 0.05181 0.9815 0.00969 0.03110 0.7554
PVL -0.28464 0.11648 0.0149* -0.00768 0.07944 0.9231
RDS -0.00964 0.09823 0.9218 -0.00429 0.01409 0.7609
ROP -0.11541 0.05215 0.0273* 0.10869 0.05649 0.0545
Atrial septal defect 0.02489 0.04802 0.6045 -0.00311 0.01872 0.8681
Ventricular septal defect 0.22274 0.11576 0.0549 0.06055 0.05134 0.2386

Abbreviations: BMI, body mass index; BPD, bronchopulmonary dysplasia; cm, centimeters; gr, grams; IVH, intraventricular hemorrhage; NEC, necrotizing enterocolitis; PDA, patent ductus arteriosus; PVL, periventricular leukomalacia; RDS, respiratory distress syndrome; ROP, retinopathy of prematurity; TPN, total parenteral nutrition

Referent groups: White maternal race, normal maternal first trimester BMI, no hypertension, no preeclampsia, singleton, no TPN, no dextrose, no BPD, no IVH, no NEC, no PDA, no PVL, no RDS, no ROP, no atrial septal defect, no ventricular septal defect.

*p<0.05. P-values were calculated using multivariable linear regression.