Table 1.
Demographic features and hematological parameters of patients with SARS‐CoV‐2 infection at the time of admission due who later developed mild or severe illness
| Characteristics | All patients (n = 68) | Mild disease (n = 22) | Severe disease (n = 46) | P value |
|---|---|---|---|---|
| Demographic features | ||||
| Age (years) | 52.4 ± 13.9 | 44.0 ± 11.3 | 56.4 ± 13.4 | <.001 |
| Gender (M/F) | 40/28 | 11/11 | 29/17 | .448 |
| Comorbidity | ||||
| Hypertension, n (%) | 18 (26.5%) | 3 (15.8%) | 15 (32.6%) | .172 |
| Diabetes, n (%) | 4 (5.9%) | 1 (4.5%) | 3 (6.5%) | .821 |
| Chronic hepatitis, n (%) | 2 (3.0%) | 0 | 2 (4.3%) | – |
| Chronic obstructive, n (%) | 1 (1.5%) | 0 | 1 (2.2%) | – |
| Bronchitis, n (%) | 1 (1.5%) | 0 | 1 (2.2%) | – |
| Renal diseases, n (%) | 4 (5.9%) | 0 | 4 (8.7%) | – |
| Cardiovascular disease, n (%) | 3 (4.4%) | 0 | 3 (6.5%) | – |
| Hematological parameters | ||||
| WBC count (× 10⁹/L) | 5.7 (4.2‐8.9) | 5.1 (3.7‐5.5) | 7.9(4.8‐10.3) | .001 |
| Neutrophil count (× 10⁹/L) | 4.4(2.8‐7.7) | 2.9 (2.5‐3.9) | 6.5 (3.6‐8.9) | <.001 |
| Lymphocyte count (× 10⁹/L) | 0.9 (0.5‐1.2) | 1.3 (0.9‐1.5) | 0.7 (0.5‐0.9) | <.001 |
| Monocyte count (× 10⁹/L) | 0.3 (0.2‐0.5) | 0.5(0.3‐0.6) | 0.3 (0.2‐0.5) | .006 |
| Platelet count (× 10⁹/L) | 201.0 ± 82.3 | 206.6 ± 74.8 | 198.4 ± 86.3 | .074 |
| Hemoglobin (g/L) | 132.6 ± 16.6 | 133.6 ± 12.5 | 131.4 ± 18.1 | .602 |
| RDW (%) | 12.4 (11.9‐13.0) | 12.4 (11.9‐12.8) | 12.4 (12.0‐13.1) | .355 |
| PCT (%) | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.2 ± 0.1 | .838 |
| NLR | 6.1 (3.3‐12.1) | 2.4 (1.4‐4.0) | 9.0 (6.0‐14.8) | <.001 |
| LMR | 2.7 (2.2‐2.9) | 2.7 (2.0‐3.7) | 2.5 (1.6‐3.3) | .409 |
| PLR | 228.6 (155.9‐337.0) | 152.2 (115.8‐233.9) | 284.0 (195.0‐441.7) | <.001 |
| MPV(fl) | 10.5 (10.1‐11.2) | 10.5 (9.7‐11.4) | 11.6 (10.1‐11.1) | .555 |
| PSI score | 55.5 (42.3‐65.8) | 5.5 (36.0‐53.8) | 61.0 (50.0‐68.0) | <.001 |
Data are expressed as number (%), mean ± SD, or median (IQR).
Abbreviations: F, female; LMR, lymphocyte‐to‐monocyte ratio; M, male; MPV, mean platelet volume; NLR, neutrophil‐to‐lymphocyte ratio; PCT, plateletcrit; PLR, platelet‐to‐lymphocyte ratio; PSI, Pneumonia Severity Index; RDW, red cell distribution width; WBC, white blood cell.