Table 2.
Reported cases of Fusobacterium nucleatum and pyogenic liver abscess
Author | Age | Sex | Immunocompetent? | Source | Treatment |
Swaminathan and Aguilar9 | 76 | F | Yes | No source identified | Percutaneous drainage Intravenous antibiotics for 4 days oral antibiotics for 4 weeks |
Zafar et al10 | 51 | M | Yes | No source identified | Percutaneous drainage—unsuccessful Intravenous antibiotics for 6 weeks |
Gohar et al11 | 54 | M | Yes | Periodontal disease considered a possible source | Tube thoracostomy for empyema Percutaneous drainage Intravenous antibiotics for 4 days Oral antibiotics for 6 weeks |
Hammami et al4 | 63 | M | Yes | Periapical dental abscess | Percutaneous drainage Extraction of problematic tooth. Antibiotics (unspecified) |
Jayasimhan et al2 | 51 | F | Not commented | Periodontal disease presumed source—nil evidence on examination (Prevotella pleuritidis also isolated) | Percutaneous drainage Intravenous antibiotics for 2 weeks Oral antibiotics for 4 weeks |
Karantanos et al12 | 43 | M | Yes | No source identified | Percutaneous drainage Intravenous antibiotics for 6 weeks Oral antibiotics for 3 months |
Wijarnpreecha et al3 | 60 | M | Yes | Diverticulitis | Percutaneous drainage Intravenous antibiotics for 5 days Oral antibiotics for 4 weeks |
Shigefuku et al13 | 78 | M | Not commented | Colonic adenocarcinoma | Percutaneous drainage Intravenous antibiotics (duration not specified) |
Kearney and Knoll14 | 23 | M | Yes | Myopericarditis | Percutaneous drainage Intravenous antibiotics for 6 weeks |
Nagpal et al7 | 69 | F | Diabetic | Periodontal disease | Percutaneous drainage Dental extractions Intravenous antibiotics for 2 weeks Oral antibiotics for 4 weeks |
Ahmed et al15 | 21 | M | Yes | Routine dental cleaning a possible cause | Percutaneous drainage Tube thoracostomy for associated pleural empyema Partial pleural decortication with a VATs procedure Percutaneous drainage of abdominal and pelvic abscesses Intravenous antibiotics for 9 weeks |
Houston et al16 | 66 | M | Yes | Diverticular perforation | Percutaneous drainage Intravenous antibiotics (duration not specified) Oral antibiotic for 6 weeks |
Schattner and Gotler17 | 58 | M | Yes | Perforated sigmoid diverticultis and pylephlebitis | Percutaneous drainage of liver abscess Laparotomy and drainage of diverticular abscess+colostomy Intravenous antibiotics for 6 weeks |
Ohyama et al18 | 59 | F | Not commented | Periodontal disease | Findings identified postmortem No treatment prior to death |
Cigarran et al19 | 58 | M | Immunocompromised | Recent dental extraction | Percutaneous drainage Intravenous antibiotics (duration not specified) Oral antibiotics for 3 weeks |
Kajiya et al20 | 59 | M | Yes | Periodontal disease+dental caries | No percutaneous drainage—patient refused Intravenous antibiotics for 4 days Oral antibiotics for 4 weeks |
Wells et al21 | 62 | M | Ulcerative colitis | Colonoscopy and biopsies | Percutaneous drainage Intravenous antibiotics (duration not specified) |
Ala et al22 | 78 | F |
Polymyalgia Rheumatica (long-term steroid treatment) |
Severe diverticular disease | Percutaneous drainage of subphrenic and intrahepatic collections Intravenous antibiotics for 6 weeks |
Crippin and Wang23 | 69 | M | Yes | Periapical periodontitis | Percutaneous drainage Antibiotics (unspecified) |
Tweedy and White24 | 29 | M | Immunocompromised | Recent routine dental work (fillings and cleaning) 4 days prior to onset of symptoms | Percutaneous drainage initially and open surgical drainage after 10 days. Intravenous antibiotics (duration not specified) Oral antibiotics for 4 weeks |