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. 2021 Jan 15;11:601785. doi: 10.3389/fphar.2020.601785

FIGURE 1.

FIGURE 1

Six strategies for cancer therapy by TCM. Traditional Chinese medicine (TCM) utilizes six principles of homeostasis and balance to treat cancer. 1) Equilibrium of immunity plays a central role in the cancer treatment by TCM. 2) TCM balances detoxification and reduces oxidative stress and inflammation. 3) TCM utilizes a strategy of vascular normalization to reduce excess angiogenesis and increase immune cells infiltration that further enhance immunotherapy. 4) TCM regulates extracellular matrix (ECM) in the tumor microenvironment. 5) Restoration of metabolic imbalance and stimulation of phlegm-eliminating and anti-inflammatory activity by TCM. 6) Reduction of psychological stress and relief of anxiety by TCM decoction. In the tumor tissue: Blue irregular cells represent tumor cells. Green and blue circle cells represent infiltrated immune cells, T lymphocyte, neutrophil, and macrophage. Red line represents blood vessels. Purple cells represent stromal cells and ECM.