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. 2020 Oct 17;11(3):683–696. doi: 10.1016/j.jcmgh.2020.10.007

Figure 5.

Figure 5

GPRP decreased VP in vivo. (A, B) A solution of 3% DSS was administered in drinking water to C57BL/6 mice for 7 days. GPRP (100 mg/kg) or distilled water was injected intraperitoneally every day for 7 days; n = 4 mice/group. Colonic VP was determined as described in the Materials and Methods. (A) Images of colons; (B) quantitative analysis. (C) Fg-induced dermal vascular leakage. (D) GPRP decreased Fg-induced dermal vascular leakage in vivo. n = 5 mice/group. For C and D, dermal VP was determined by miles permeability assay as described in the Materials and Methods. Analysis of relative VP were displayed below. Data are presented as mean ± SEM. ∗∗P < .01; ∗∗∗P < .001 (2-tailed unpaired Student’s t test).