Table 1.
Comparison with previous reports
| Study | Country | Year | Race | High-risk or sporadic | Total | BRCA1+ | BRCA2+ | BRCA1/2+ | Reference | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | (%) | Cases | (%) | Cases | (%) | |||||||
| Sugano et al. | Japan | 2008 | Japanese | h | 122 | 16 | (13.1) | 18 | (14.8) | 34 | (27.9) | [23] |
| Hall et al. | USA | 2009 | Mixed | h | 46,276 | 3351 | (7.2) | 2444 | (5.3) | 5795 | (12.5) | [26] |
| Weitzel et al. | USA | 2012 | Mixed | h | 746 | 124 | (16.6) | 65 | (8.7) | 189 | (25.3) | [27] |
| Couch et al. | USA | 2015 | Mixed | h | 1824 | 155 | (8.5) | 49 | (2.7) | 204 | (11.2) | [25] |
| Kang et al. | South Korea | 2015 | Korean | h | 2403 | 157 | (6.5) | 224 | (9.3) | 378 | (15.7) | [31] |
| Kast et al. | Germany | 2016 | Germany | h | 59,304 | 10,195 | (17.2) | 5542 | (9.3) | 15,737 | (26.5) | [32] |
| Kemp et al. | UK | 2019 | NA | h | 1184 | 57 | (4.8) | 60 | (5.1) | 117 | (9.9) | [37] |
| Okano et al. | Japan | 2020 | Japanese | h | 2,366 | 262 | (11.1) | 211 | (8.9) | 476 | (20.1) | |
| Tung et al. | USA | 2015 | Mixed | mixed | 1,781 | 78 | (4.4) | 87 | (4.9) | 165 | (9.3) | [30] |
| Buys et al. | USA | 2017 | Mixed | mixed | 35,409 | 814 | (2.3) | 828 | (2.3) | 1642 | (4.6) | [34] |
| Palomba et al. | Italy | 2014 | Italian | s | 726 | 7 | (1.0) | 14 | (1.9) | 21 | (2.9) | [28] |
| Ghadirian et al. | Canada | 2014 | French-Canadian | s | 1093 | 13 | (1.2) | 43 | (3.9) | 56 | (5.1) | [29] |
| Susswein et al. | USA | 2016 | Mixed | s | 5209 | 63 | (1.2) | 73 | (1.4) | 136 | (2.6) | [33] |
| Wen et al. | Malaysia | 2017 | Asian | s | 2575 | 55 | (2.1) | 66 | (2.6) | 121 | (4.7) | [35] |
| Momozawa et al. | Japan | 2018 | Japanese | s | 7051 | 102 | (1.45) | 191 | (2.71) | 293 | (4.16) | [36] |