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. 2021 Jan 15;8:601649. doi: 10.3389/fchem.2020.601649

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Copyright © 2021 Zhao, Wang, Zheng, Zeng, Lim and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cell migration behavior after treatment of PEG-PLGA-Cur, PEG-PLGA-Sal, PEG-PLGA, Cur, and Sal against CSCs using wound healing assay: (A) wound closure length, (B) wound closure rate, and (C) percentage of confluency of wound healing assay. (D) Expression of epithelial–mesenchymal transition markers of HA-PEG-PLGA-Cur-Sal, PEG-PLGA-Cur-Sal, free Cur + free Sal, Cur, and Sal. Values are means ± standard deviations (n = 5, S.D.) (**p < 0.01, ****p < 0.0001).