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. 2021 Jan 15;11:615887. doi: 10.3389/fmicb.2020.615887

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Copyright © 2021 Son, Kong, Lee and Ryu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lytic activity comparison of Lys109 with parental endolysins. (A) Comparison of the relative lytic activity of four other chimeric endolysins and LysSA12 with Lys109 (300 nM each) against S. aureus CCARM 3090. (B) Schematic representation of Lys109, LysSA12 and LysSA97. (C) SDS-PAGE analysis of Lys109, LysSA12, and LysSA97. (D) Relative lytic activity of Lys109, LysSA12 and LysSA97 against S. aureus CCARM 3090 at different concentrations. (E) Relative lytic activity of Lys109, LysSA12 and LysSA97 (300 nM each) against various S. aureus strains. (F) MIC values of Lys109, LysSA12 and LysSA97 against S. aureus CCARM 3090.