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. 2021 Jan 15;7:625579. doi: 10.3389/fcvm.2020.625579

Table 2.

Selected studies on bacteremia of periodontal pathogens and periodontal pathogens identified in atheromatous lesions in subjects with chronic periodontitis.

References Design Technique Intervention Bacterial species (prevalence)
Forner et al. (82)a C-S Lysis filtration Chewing gum and tooth brushing Pg (10), Pi (40%), Fn (40%)
Lafaurie et al. (83)a C-S Culture SRP Pg (28.5%), Tf (7.1%), Fn (11.9%)
Perez-Chaparro et al. (84)a C-S Culture SRP Pg (43.7%)
Castillo et al. (85)a C-S Nested PCR SRP Pg (31%), Aa (21.4)
Waghmare et al. (86)a C-S Culture SRP Pg (37.5%), Pi (15%), Tf (12.5%)
Sharmann et al. (87)a RCT Lysis centrifugation, culture SRP and povidone iodine Pi (5.2%), Fn (5.2%)
Marin et al. (88)a C-S Lysis centrifugation, culture, qPCR Tooth brushing Fn (33%)
Balejo et al. (79)a RCT Culture, qPCR SRP and chlorhexidine Pg (Change in levels. By culture from 113.8 to 782.4, by qPCR from 0.5 to 512.5)
Elkaim et al. (89)b C-S Hybridization None Aa (54.4%), Pg (72.7%),
Nakano et al. (33)b C-S Specific PCR None Aa (35%), Pg (20%), Td (20%)
Gaetti- Jardim et al. (90)b C-S Real time PCR None Aa (46.2%), Pg (53.8%), Tf (25.6%), Pi (59%), Fn (0)
Figuero et al. (91)b C-S Nested PCR None Aa (66.7%), Pg (78.6%), Tf (61.9%), Fn (50%)
a

Bacteremia after periodontal procedure.

b

Periodontal pathogen in atheromatous lesion. C-S, cross sectional; SRP, scaling and root planing; RCT, randomized clinical trial; Pg, Porphyromonas gingivalis; Tf, Tannerella forsythia; Td, Treponema denticola; Pi, Prevotella intermedia; Aa, Aggregatibacter actinomycetemcomitans; Fn, Fusobacterium nucleatum; FISH, florescence in situ hybridization; qPCR, quantitative polymerase chain reaction.