TABLE 2.
Strains | β -lactamase |
No. of positive tests/total no. of strains |
Sensitivity [% (95% CI)] | Specificity [% (95% CI)] | ||
NG-test Carba 5 | RESIST-5 O.O.K.N.V. | IMP K-SeT | ||||
Clinical strains | ||||||
KPC-2 | 70/70 | 70/70 | 0/70 | 100 (93.5–100) | 100 (96.0–100) | |
NDM | 60/60 | 100 (92.5–100) | 100 (96.3–100) | |||
59/60 | 0/60 | 98.3 (89.7–100) | 100 (96.3–100) | |||
NDM-1 | 35/35 | 34/35 | ||||
NDM-5 | 23/23 | 23/23 | ||||
NDM-7 | 1/1 | 1/1 | ||||
NDM-9 | 1/1 | 1/1 | ||||
IMP | 6/6 | 0/6 | 6/6 | 100 (51.7–100) | 100 (97.4–100) | |
IMP-4 | 5/5 | 0/5 | 5/5 | |||
IMP-6 | 1/1 | 0/1 | 1/1 | |||
OXA-48-like | 24/24 | 24/24 | 0/24 | 100 (82.8–100) | 100 (97.1–100) | |
OXA-232 | 20/20 | 20/20 | ||||
OXA-48 | 2/2 | 2/2 | ||||
OXA-181 | 2/2 | 2/2 | ||||
VIM-1 | 1/1 | 1/1 | 0/1 | 100 (5.5–100) | 100 (97.5–100) | |
Multiple carbapenemases | 11/11 | 11/11 | 2/11 | 100 (67.9–100) | 100 (97.3–100) | |
KPC-2 + NDM-1 | 7/7 | 7/7 | ||||
KPC-2 NDM-5 | 1/1 | 1/1 | ||||
NDM-5 OXA-48 | 1/1 | 1/1 | ||||
NDM-1 IMP-4 | 1/1 | 1/1 | ||||
NDM-1 IMP-6 | 1/1 | 1/1 | ||||
Carbapenemase-negative | 0/14 | 0/14 | 0/14 | |||
Total | 172/186 | 100 (97.3–100) | 100 (73.2–100) | |||
165/186 | 6/186 | 99.4 (96.2–100) | 100 (80.0–100) | |||
Reference strains | ||||||
KPC-2 | 14/14 | 14/14 | 0/14 | |||
NDM-1 | 6/6 | 6/6 | 0/6 | |||
IMP-1/70 | 1/1 | 0/1 | 1/1 | |||
VIM-1 | 2/2 | 2/2 | 0/2 | |||
OXA-48-like | 3/3 | 3/3 | 0/3 | |||
OXA-48 | 2/2 | 2/2 | ||||
OXA-181 | 1/1 | 1/1 | ||||
ESBL | 0/3 | 0/3 | 0/3 | |||
Total | 26/29 | 100 (84.0–100) | 100 (31.0–100) | |||
25/29 | 1/1 | 100 (83.4–100) | 100 (39.6–100) |