TABLE 1.
Patients with AD | Patients with MCI | Control subjects | p-value | |
(n = 62) | (n = 47) | (n = 49) | ||
Age | 71.81 ± 7.98 | 72.73 ± 7.75 | 69.50 ± 5.94 | 0.079 |
Medium (range) | 73 (57, 89) | 74 (53, 87) | 71 (57, 81) | |
Sex (M/F) | 27/35 | 18/29 | 17/32 | 0.634 |
VA | 0.68 ± 0.25 | 0.75 ± 0.22 | 0.70 ± 0.14 | 0.275 |
IOP (mmHg) | 14.24 ± 2.55 | 14.62 ± 2.57 | 14.26 ± 2.20 | 0.718 |
HBP | 22 | 19 | 18 | 0.865 |
DM | 8 | 8 | 8 | 0.812 |
MMSE score | 19.92 ± 4.54 | 28.04 ± 1.90 | 28.67 ± 1.0 | <0.001** |
Medium (range) | 20 (7, 24) | 28 (23, 30) | 29 (27, 30) | |
CDR global | 1.339 ± 0.061 | 0.532 ± 0.018 | 0.031 ± 0.017 | <0.001** |
MTA | 1.77 ± 0.231 | 1.34 ± 0.143 | 0.89 ± 0.200 | 0.071 |
Fazekas | 0.88 ± 0.234 | 0.71 ± 0.137 | 0.56 ± 0.176 | 0.598 |
GCA | 1.46 ± 0.144 | 1.14 ± 0.147 | 0.780 ± 0.147 | 0.108 |
PCA | 1.08 ± 0.178 | 0.76 ± 0.137 | 0.44 ± 0.176 | 0.257 |
Data reported as mean and SD (standard deviation) with p values. AD, Alzheimer’s disease; MCI, mild cognitive impairment; M, male; F, female; VA, visual acuity; IOP, intraocular pressure; HBP, high blood pressure; DM, diabetes mellitus; MMSE, Mini–Mental State Examination; CDR, clinical dementia rating, the global score of CDR was used. The bold values indicate statistical significance. **p < 0.01.