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. 2021 Jan 15;12:572484. doi: 10.3389/fnagi.2020.572484

TABLE 1.

Demographic and clinical characteristics of the study subjects.

Patients with AD Patients with MCI Control subjects p-value



(n = 62) (n = 47) (n = 49)
Age 71.81 ± 7.98 72.73 ± 7.75 69.50 ± 5.94 0.079
Medium (range) 73 (57, 89) 74 (53, 87) 71 (57, 81)
Sex (M/F) 27/35 18/29 17/32 0.634
VA 0.68 ± 0.25 0.75 ± 0.22 0.70 ± 0.14 0.275
IOP (mmHg) 14.24 ± 2.55 14.62 ± 2.57 14.26 ± 2.20 0.718
HBP 22 19 18 0.865
DM 8 8 8 0.812
MMSE score 19.92 ± 4.54 28.04 ± 1.90 28.67 ± 1.0 <0.001**
Medium (range) 20 (7, 24) 28 (23, 30) 29 (27, 30)
CDR global 1.339 ± 0.061 0.532 ± 0.018 0.031 ± 0.017 <0.001**
MTA 1.77 ± 0.231 1.34 ± 0.143 0.89 ± 0.200 0.071
Fazekas 0.88 ± 0.234 0.71 ± 0.137 0.56 ± 0.176 0.598
GCA 1.46 ± 0.144 1.14 ± 0.147 0.780 ± 0.147 0.108
PCA 1.08 ± 0.178 0.76 ± 0.137 0.44 ± 0.176 0.257

Data reported as mean and SD (standard deviation) with p values. AD, Alzheimer’s disease; MCI, mild cognitive impairment; M, male; F, female; VA, visual acuity; IOP, intraocular pressure; HBP, high blood pressure; DM, diabetes mellitus; MMSE, Mini–Mental State Examination; CDR, clinical dementia rating, the global score of CDR was used. The bold values indicate statistical significance. **p < 0.01.