TABLE 3.

Multivariate analysis of retinal vascular density.

	AD versus HC			MCI versus HC
	β	95% CI	p-value	β	95% CI	p-value
OCT-A deep
Whole enface	–0.2616	(−0.8053, 0.2821)	0.3456	–0.7413	(−1.7874, 0.3049)	0.1649
Superior	–0.2539	(−0.8085, 0.3007)	0.3695	–0.7088	(−1.7471, 0.3294)	0.1809
Inferior	–0.2365	(−0.7966, 0.3237)	0.4080	–0.7479	(−1.8377, 0.3418)	0.1786
Fovea	–0.0276	(−1.3514, 1.2962)	0.9674	–2.3619	(−5.1648, 0.4410)	0.0986
Parafovea	–0.2793	(−0.8427, 0.2840)	0.3311	–0.5114	(−1.5594, 0.5365)	0.3388
OCT-A superficial
Whole enface	–0.7020	(−1.2254, −0.1787)	0.0086**	–2.0889	(−2.9873, −1.1906)	<0.0001**
Superior	–0.7614	(−1.2756, −0.2472)	0.0037**	–1.9547	(−2.8576, −1.0518)	<0.0001**
Inferior	–0.6394	(−1.2015, −0.0774)	0.0258*	–2.2304	(−3.1875, −1.2734)	<0.0001**
Fovea	0.0082	(−1.0325, 1.0488)	0.9877	–2.1499	(−4.2692, −0.0306)	0.0468*
Parafovea	–0.6451	(−1.2228, −0.0673)	0.0286*	–1.9629	(−2.9529, −0.9730)	0.0001**
OCT-A disk
Whole enface	0.1561	(−1.1079, 1.4202)	0.8087	0.6946	(−1.4836, 2.8728)	0.5320
Peripapillary	–0.3611	(−0.9918, 0.2697)	0.2619	–0.5785	(−1.7105, 0.5534)	0.3165

A generalized linear model was used to evaluate the relationship between retinal measures and clinical diagnosis, which was adjusted for confounders of sex, age, medical history of hypertension and diabetes, and the quality index of OCTA image. The scale parameter was estimated by maximum likelihood. The bold values indicate statistical significance. *p < 0.05 and **p < 0.01.