Table 1.
Evaluation time points.
| T0° | T1° | T2° | T3° | T4° | |
|---|---|---|---|---|---|
| First week | 3 months | 6 months | 9 months | 12 months | |
| Informed consent | ✓ | ||||
| Inclusion and exclusion criteria | ✓ | ||||
| Clinical history | ✓ | ||||
| Fugl-Meyer Assessment | ✓ | ✓ | ✓ | ✓ | ✓ |
| Oxford Cognitive Screen | ✓ | ✓ | ✓ | ✓ | ✓ |
| Barthel Index | ✓ | ✓ | ✓ | ✓ | ✓ |
| Volumetric analysis of the stroke | ✓ | ||||
| Side and site of stroke | ✓ | ||||
| DTI | ✓ | ||||
| fMRI | ✓ | ✓ | |||
| MEP and cortical excitability to TMS | ✓ | ✓ | |||
| SSEP | ✓ | ✓ | |||
| EEG | ✓ | ✓ | |||
| MFI | ✓ | ✓ | |||
| DEXA | ✓ | ||||
| Microbiota | ✓ | ||||
| Biochemistry and miRNA analysis | ✓ | ✓ | |||
| Usual care | ✓ | ✓ | ✓ | ✓ | ✓ |
| Intensive self-rehabilitation program | ✓ | ✓ | ✓ | ✓ | ✓ |
| Physiatric evaluation | ✓ | ✓ | ✓ | ✓ | ✓ |
| Video analysis and energetic cost of the gait | ✓ | ✓ | ✓ | ✓ | ✓ |
| Psychological evaluation scales | ✓ | ✓ | ✓ | ✓ | ✓ |
| Informed consent | ✓ | ✓ | ✓ | ✓ | ✓ |
DTI, Diffusion Tensor Imaging; fMRI, functional Magnetic Resonance Image; MEP, Motor evoked potential; SEP, Somatosensory evoked potential; TMS, Transcranial Magnetic Stimulation; EEG, Electroencephalography; MFI, Multidimensional Fatigue Inventory; DEXA, Dual X-ray Absorptiometry; miRNA, microRNA. °Time from the enrollment.