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Summary of glioma-immune interactions. Gliomas secrete or express a variety of factors that attract or induce immunosuppressive cell types, or have direct inhibitory effects on immune effector cells. T Eff effector T cell, ROS reactive oxygen species, NO nitric oxide, GAM glioma-associated microglia/macrophage, MDSC myeloid-derived suppressor cell, T reg regulatory T cell, MHC major histocompatibility complex, APC antigen presenting cell. Created with BioRender.com
