Table 1.

Aortic stenosis quantification and associated calcification

Echocardiography and MSCT M = male; F = female	AVA > 1.0 cm2 (n = 97) M = 53; F = 44	p value	AVA ≤ 1.0 cm2 (n = 841) M = 390; F = 451	p value	pAS-severity
M AVA, cm2	1.2 ± 0.1	0.069	0.7 ± 0.2	< 0.0001*	< 0.0001*
F AVA, cm2	1.1 ± 0.1		0.7 ± 0.2		< 0.0001*
M dPmean, mmHg	25.1 ± 8.8	0.359	37.1 ± 15.0	0.007*	< 0.0001*
F dPmean, mmHg	23.4 ± 9.6		40.1 ± 16.6		< 0.0001*
M LVEF, %	49.5 ± 14.6	0.007*	52.2 ± 13.3	< 0.0001*	0.292
F LVEF, %	60.5 ± 14.5		58.0 ± 12.5		0.334
M AVC, AU	1365 [827–2106]	< 0.0001*	2245 [1418–3340]	< 0.0001*	< 0.0001*
F AVC, AU	642 [407–1124]		1388 [772–2187]		< 0.0001*
M AVC density, AU/cm2	228 [162–411]	0.002*	414 [265–602]	< 0.0001*	< 0.0001*
F AVC density, AU/cm2	157 [98–243]		322 [184–492]		< 0.0001*
M NCC, AU	482 [283–1025]	< 0.0001*	868 [502–1364]	< 0.0001*	0.001*
F NCC, AU	241 [89–433]		572 [268–1042]		< 0.0001*
M NCC density, AU/cm2	95 [54–173]	0.001*	158 [95–253]	0.001*	< 0.0001*
F NCC density, AU/cm2	49 [25–104]		132 [65–235]		< 0.0001*
M RCC, AU	361 [159–641]	< 0.0001*	641 [362–1085]	< 0.0001*	< 0.0001*
F RCC, AU	170 [48–360]		364 [200–652]		< 0.0001*
M RCC density, AU/cm2	65 [29–131]	0.019*	113 [65–195]	< 0.0001*	< 0.0001*
F RCC density, AU/cm2	45 [12–76]		83 [44–155]		< 0.0001*
M LCC, AU	330 [160–571]	0.002*	607 [329–1032]	< 0.0001*	< 0.0001*
F LCC, AU	193 [79–309]		326 [165–626]		0.0001*
M LCC density, AU/cm2	65 [36–100]	0.055	111 [61–178]	< 0.0001*	< 0.0001*
F LCC density, AU/cm2	46 [21–71]		79 [38–145]		< 0.0001*
M LVOT, AU	15 [0–157]	0.202	32 [0–176]	0.820	0.661
F LVOT, AU	4 [0–75]		34 [2–189]		0.027*
M LVOT density, AU/cm2	4 [0–24]	0.272	6 [0–30]	0.266	0.623
F LVOT density, AU/cm2	1 [0–19]		6 [0–42]		0.023*

Values are mean ± SD, median ± interquartile range or n (%)

AVA aortic valve area, AVC aortic valve calcification, AU Agatston units, dPmean mean transvalvular gradient, LCC left coronary cusp, LVEF left-ventricular ejection fraction, LVOT left -ventricular outflow tract, NCC non-coronary cusp, RCC right coronary cusp

* p < 0.05