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. 2020 Sep 4;259(2):449–458. doi: 10.1007/s00417-020-04900-8

Fig. 1.

Fig. 1

Activation of iNOS transcription through NF-κB binding at the iNOS promotor region. The scheme displays the activation of NF-κB by IFN-γ, LPS, TNF-α, or IL-1β. NF-κB can directly bind to the iNOS promotor region to activate the transcription of iNOS which is able to start the production of nitric oxide