Table 4.
I | Inotropes | Previous or ongoing requirement for dobutamine, milrinone, dopamine or levosimandan |
N | NYHA classification/Natriuretic peptides | Persisting NYHA class III or IV and/or persisting high BNP or NT-proBNP |
E | End-organ dysfunction | Worsening renal or liver dysfunction in the setting of heart failure |
E | Ejection fraction | Very low ejection fraction <20% |
D | Defibrillation shocks | Recurrent appropriate defibrillator shocks |
H | Hospitalisations | More than 1 hospitalisation for heart failure in the last 12 months |
E | Edema/Escalating diuretics | Persisting fluid overload and/or increasing diuretic requirement |
L | Low blood pressure | Consistently low BP with a systolic <90–100 mm Hg |
P | Prognostic medication | Inability to up-titrate (or need to decrease or cease) ACEI, β‑blockers, ARNIs or MRAs |
(Adapted from [20] with permission)
ACEI angiotensin-converting enzyme inhibitor, ARNI angiotensin-receptor neprilysin inhibitor, BNP B-type natriuretic peptide, BP blood pressure, MRA mineralocorticoid receptor antagonist, NT-proBNP N-terminal pro-b-type natriuretic peptide, NYHA New York Heart Association