. 2020 Nov 24;19(2):1599–1607. doi: 10.1007/s40200-020-00699-7

Table 2.

Effect of POL and POL-NPs on renal function related parameters in STZ-induced diabetic rats

Group	BUN (mg/dl)	SCr (mg/dl)	Uric acid (mg/dl)	Albumin (g/dl)
Parameter	BUN (mg/dl)	SCr (mg/dl)	Uric acid (mg/dl)	Albumin (g/dl)
Control	14.33 ± 0.52	0.43 ± 0.03	4.21 ± 0.18	3.96 ± 0.17
Diabetic	26.66 ± 0.97***	0.69 ± 0.02***	6.24 ± 0.15 ***	2.19 ± 0.10***
Diabetic + POL	19.17 ± 0.70⁺⁺⁺	0.56 ± 0.08⁺⁺⁺	5.10 ± 0.09⁺⁺⁺	3.24 ± 0.12⁺⁺⁺
Diabetic + POL-NPs	18.90 ± 0.64⁺⁺⁺	0.54 ± 0.03⁺⁺⁺	4.97 ± 0.20 ⁺⁺⁺	3.57 ± 0.13⁺⁺⁺

Values were expressed as mean ± standard error. ***P < 0.001, compared with normal control group. ⁺⁺⁺P < 0.001, compared with diabetic group. STZ: streptozotocin, POL: polydatin, POL-NPs: polydatin-loaded chitosan nanoparticles, SCr: serum creatinine, BUN: blood urea nitrogen