. 2020 Nov 24;19(2):1599–1607. doi: 10.1007/s40200-020-00699-7

Table 3.

Effect of POL and POL-NPs on kidney oxidative stress and antioxidant enzymes in STZ-induced diabetic rats

Group	LPO (nmol MDA/100 mg protein)	SOD (U/g protein)	CAT (U/mg protein)	GSH (nmol/100 mg protein)
Parameter	LPO (nmol MDA/100 mg protein)	SOD (U/g protein)	CAT (U/mg protein)	GSH (nmol/100 mg protein)
Control	14.37 ± 1.10	7.33 ± 0.50	118.80 ± 0.94	76.63 ± 5.55
Diabetic	68.87 ± 3.08***	1.50 ± 0.16***	55.57 ± 1.47***	25.47 ± 1.44***
Diabetic + POL	29.27 ± 0.48⁺⁺⁺	4.70 ± 0.73⁺⁺⁺	95.33 ± 3.21⁺⁺⁺	51.40 ± 1.67⁺⁺⁺
Diabetic + POL-NPs	18.98 ± 0.60^+++$$$	6.03 ± 0.50^+++$$	108.13 ± 2.15^+++$$$	67.13 ± 2.62^+++$$

Values were expressed as mean ± standard error. ***P < 0.001, compared with normal control group. ⁺⁺⁺P < 0.001, compared with diabetic group. ^$$P < 0.01, ^$$$P < 0.001, compared with diabetic group treated with POL (Diabetic + POL). STZ: streptozotocin, POL: polydatin, POL-NPs: polydatin-loaded chitosan nanoparticles, LPO: Lipid peroxidation, MDA: malonaldehyde, SOD: superoxide dismutase, CAT: catalase, GSH: glutathione