Table 2.
The effects of L-carnitine supplementation on biomarkers of inflammation and oxidative stress
| Variables | Number of effect sizes | Weighted mean difference | CI 95% | Heterogeneity | |
|---|---|---|---|---|---|
| I2 (%) | P- value heterogeneity | ||||
| CRP | 30 | -0.10 | -0.14, -0.06 | 93.2 | < 0.001 |
| IL-6 | 13 | -1.87 | -2.80, -0.95 | 93.4 | < 0.001 |
| TNF-α | 13 | -1.43 | -2.03, -0.84 | 98.0 | < 0.001 |
| GPx | 6 | 0.02 | -0.01, 0.05 | 91.4 | < 0.001 |
| SOD | 6 | 2.14 | 1.02, 3.25 | 96.2 | < 0.001 |
| TAC | 9 | 0.14 | -0.05, 0.33 | 97.1 | < 0.001 |
| MDA | 14 | -0.47 | -0.76, -0.18 | 98.2 | < 0.001 |
CRP: C-reactive protein; IL-6: Interleukin-6; TNF-α: Tumor Necrosis Factor-α; GPx: Glutathione Peroxidase; SOD: Superoxide dismutase; TAC: Total Antioxidant Capacity; MDA: Malondialdehyde