Table 3.
Effect of the AECPLS on the lipid profile and cardiovascular indices of insulin resistant rats
| Groups | Normal control | Diabetic control | Dexa + Met (40 mg/kg) | Dexa + Extract (mg/kg) | ||
|---|---|---|---|---|---|---|
| 111 | 222 | 444 | ||||
| TC (mg/dL) | 111.51 ± 4.94 | 116.13 ± 3.39 | 111.64 ± 2.94 | 107.21 ± 3.04 | 106.96 ± 4.70 | 103.54 ± 2.03 |
| TG (mg/dL) | 86.86 ± 1.59 | 118.42 ± 5.76*** | 92.60 ± 3.49b | 99.69 ± 5.33a | 97.44 ± 5.07a | 93.50 ± 4.49a |
| HDL-c (mg/dL) | 57.36 ± 1.27 | 34.26 ± 2.66*** | 5033 ± 2.20b | 45.44 ± 3.49a | 46.75 ± 2.37a | 48.2 ± 1.92b |
| LDL-c (mg/dL) | 35.23 ± 3.70 | 62.11 ± 3.06*** | 42.78 ± 4.35a | 45.00 ± 4.37a | 43.79 ± 4.52a | 36.64 ± 2.49b |
| AI | 0.18 ± 0.15 | 0.53 ± 0.02*** | 0.26 ± 0.08c | 0.34 ± 0.07b | 0.31 ± 0.17b | 0.28 ± 0.12c |
| CRI | 1.89 ± 0.06 | 3.62 ± 0.12*** | 2.23 ± 0.12c | 2.60 ± 0.18c | 2.47 ± 0.17c | 2.15 ± 0.08c |
| CI | 1.75 ± 0.20 | 0.52 ± 0.02*** | 1.24 ± 0.17a | 1.03 ± 0.24a | 1.06 ± 0.17a | 1.35 ± 0.13b |
Values are expressed as mean ± SD (n = 5). *** p < 0.001 compared to the normal control group. ap < 0.05; bp < 0.01; cp < 0.001 compared to the diabetic control group. Dexa: dexamethasone; Met: metformin; Ext: extract.