Table 1.
Baseline characteristics of the study population
| Overall | Group 1 | Group 2 | Group 3 | p-value | ||
|---|---|---|---|---|---|---|
| (1987–1994) | (1995–2002) | (2003–2010) | ||||
| n = 206 | n = 59 | n = 58 | n = 89 | |||
| Age at intervention (days) | 30 (2–6413) | 35 (2–5579) | 28 (4–5231) | 26 (5–6413) | 0.54 | |
| Infants | 159 (77%) | 48 (81%) | 46 (79%) | 65 (73%) | 0.45 | |
| Young children | 36 (17%) | 10 (17%) | 9 (16%) | 17 (19%) | 0.85 | |
| Adolescents | 11 (5%) | 1 (2%) | 3 (5%) | 7 (8%) | 0.26 | |
| Intervention <3 months of age | 135 (66%) | 40 (68%) | 38 (66%) | 57 (64%) | 0.90 | |
| Age at study (years) | 15.5 (7.0–35.5) | 22.7 (7.0–30.8) | 17.4 (7.0–35.5) | 11.0 (7.0–25.3) | <0.01 | |
| Sex (male) | 137 (67%) | 36 (61%) | 42 (72%) | 57 (64%) | 0.93 | |
| Follow-up (months) | 152 (75–347) | 268 (83–347) | 205 (79–274) | 117 (75–166) | <0.01 | |
| Associated lesions | 147 (71%) | 42 (71%) | 38 (65%) | 67(75%) | 0.38 | |
| Bicuspid aortic valve | 80 (39%) | 22 (37%) | 22 (38%) | 36 (40%) | 0.92 | |
| Hypoplastic aortic arch | 43 (21%) | 6 (10%) | 8 (14%) | 29 (33%) | <0.01 | |
| Ventricular septal defect | 78 (38%) | 24 (41%) | 19 (33%) | 35 (39%) | 0.63 | |
| Patent ductus arteriosus | 44 (21%) | 16 (27%) | 3 (5%) | 25 (28%) | <0.01 | |
| Haemodynamically significant comorbiditya | 114 (55%) | 31 (53%) | 23 (40%) | 59 (66%) | <0.01 | |
Data are presented as median (range) or number of patients (percentage)
Group 1, treatment between 1987 and 1995. Group 2, treatment between 1996 and 2002. Group 3, treatment between 2003 and 2010
aHaemodynamically significant comorbidity requiring repair