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. 2020 Oct 24;12(1):171–181. doi: 10.1007/s13300-020-00948-1
Why carry out this study?
Thiazolidinediones (TZDs) decrease urinary albumin excretion and improve albuminuria values in patients with type 2 diabetes mellitus (T2DM).
Lobeglitazone, a novel TZD developed in Korea, has been used in patients with T2DM.
To date, no study has assessed the efficacy of lobeglitazone on albuminuria
What was learned from the study?
This is the first study to evaluate the efficacy of lobeglitazone on albuminuria for 24 weeks in patients with T2DM, in comparison to pioglitazone.
Lobeglitazone was shown to have a tendency to improve albuminuria in patients with T2DM and had comparable effects on albuminuria as pioglitazone which has demonstrated beneficial effects.