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. 2020 Jun 23;19(2):783–804. doi: 10.1007/s40200-020-00564-7

Table 3.

Top 20 of Molecular function obtain from enrichment of PPA- AD common genes. Observed gene count indicate the number of genes from our list and background gene count indicate the number of genes allocated to the specific GO term in its library

Gene Onthology ID Description Observed gene count Background gene count False discovery rate
GO:0005515 protein binding 221 6605 2.27E-48
GO:0005488 binding 266 11878 1.97E-34
GO:0005102 signaling receptor binding 87 1513 2.28E-26
GO:0019899 enzyme binding 98 2197 2.95E-22
GO:0004672 protein kinase activity 46 635 2.48E-16
GO:0016773 phosphotransferase activity, alcohol group as acceptor 50 767 3.44E-16
GO:0044877 protein-containing complex binding 54 968 6.79E-15
GO:0016301 kinase activity 50 835 6.97E-15
GO:0019900 kinase binding 44 678 3.82E-14
GO:0042802 identical protein binding 72 1754 8.55E-14
GO:0019901 protein kinase binding 40 599 3.29E-13
GO:0098772 molecular function regulator 69 1793 6.63E-12
GO:0008134 transcription factor binding 38 610 1.05E-11
GO:0004713 protein tyrosine kinase activity 22 180 1.08E-11
GO:0003824 catalytic activity 140 5592 1.43E-11
GO:0043167 ion binding 145 6066 1.44E-10
GO:0043168 anion binding 85 2696 1.44E-10
GO:0140096 catalytic activity, acting on a protein 74 2176 1.77E-10
GO:0008144 drug binding 63 1710 4.28E-10
GO:0097367 carbohydrate derivative binding 72 2163 9.22E-10