Table 4.

Top 20 of cellular component enrichment detected from common AD-PPA genes. Observed gene count indicate the number of genes from our list and background gene count indicate the number of genes allocated to the specific GO term in its library

Gene Onthology ID	Description	Observed gene count	Background gene count	False discovery rate
GO:0044444	cytoplasmic part	214	9377	4.25E-18
GO:0005576	extracellular region	97	2505	1.46E-17
GO:0005737	cytoplasm	235	11238	2.71E-17
GO:0009986	cell surface	49	690	2.71E-17
GO:0005615	extracellular space	62	1134	4.48E-17
GO:0044421	extracellular region part	68	1375	7.88E-17
GO:0031982	vesicle	90	2318	1.44E-16
GO:0044459	plasma membrane part	95	2651	1.71E-15
GO:0005829	cytosol	138	4958	3.91E-15
GO:0031410	cytoplasmic vesicle	83	2226	3.69E-14
GO:0071944	cell periphery	139	5254	1.63E-13
GO:0005886	plasma membrane	137	5159	2.17E-13
GO:0044464	cell part	277	16244	3.10E-13
GO:0012505	endomembrane system	120	4347	2.48E-12
GO:0098805	whole membrane	63	1554	5.50E-12
GO:0045121	membrane raft	27	300	8.19E-12
GO:0044422	organelle part	191	9111	6.90E-11
GO:0043227	membrane-bounded organelle	219	11244	1.20E-10
GO:0044446	intracellular organelle part	187	8882	1.20E-10
GO:0005622	intracellular	254	14286	2.61E-10