Table 3.
Effects of N. gaditana on biochemical parameters
| Parameters | Control rats | Diabetic rats | P (ANOVA) | ||
|---|---|---|---|---|---|
| C | CM | D | DM | ||
| Glucose (g/L) | 1.17 ± 0.01c | 1.20 ± 0.04c | 4.41 ± 0.08a | 2.44 ± 0.02b | 0.010 |
| HbA1c (%) | 4.40 ± 0.14c | 4.10 ± 0.2c | 10.70 ± 0.87a | 9.60 ± 0.7b | 0.004 |
| Triglycerides (g/L) | 1.15 ± 0.01c | 1.10 ± 0.01c | 2.28 ± 0.04a | 1.94 ± 0.03b | 0.006 |
| Cholesterol (g/L) | 1.53 ± 0.01c | 1.44 ± 0.01c | 2.43 ± 0.04a | 2.02 ± 0.03b | 0.004 |
| ALT (IU/L) | 42.45 ± 1.47c | 40.71 ± 1.47c | 52.94 ± 0.88a | 48.51 ± 1.91b | 0.010 |
| AST (IU/L) | 36.86 ± 4.00c | 30.8 ± 4.00c | 50.51 ± 0.71a | 41.94 ± 0.03b | 0.007 |
| ALP (IU/L) | 83.35 ± 4.15b | 81.14 ± 4.15b | 90.33 ± 3.83a | 84.16 ± 3.48b | 0.006 |
| LDH (IU/L) | 323.41 ± 159.42c | 314.38 ± 166.70c | 655.85 ± 191.06a | 462.13 ± 286.72b | 0.033 |
| Uric acid (mg/dL) | 35.38 ± 0.93c | 39.18 ± 1.64b | 72.76 ± 1.82a | 39.44 ± 2.73b | 0.010 |
| Urea (mg/dL) | 36.62 ± 1.95c | 36.15 ± 3.24c | 41.26 ± 2.72a | 38.45 ± 1.83b | 0.010 |
| Creatinine (mg/dL) | 65.90 ± 5.55c | 64.54 ± 2.07c | 90.26 ± 3.29a | 87.73 ± 3.25b | 0.010 |
Values are presented as means ± SD (Standart deviation). Values with different superscript letters (a, b, c, d) are significantly different (ANOVA). HbA1c glycated hemoglobin, ALT alanine aminotransferase, AST aspartate aminotransferase, ALP alkaline phosphatase, LDH lactate dehydrogenase
C normal rats fed a control diet, CM normal rats fed a control diet enriched with microalgae at 10%, D diabetic rats fed only with control diet, DM diabetic rats fed a control diet enriched with microalgae at 10%