Table 2.
Effect of phenolic-rich extracts of A. paniculata on liver function markers in alloxan-induced diabetic rats
| Groups | ALT (U/l) | AST (U/l) | ALP (U/l) | T. Protein (g/dl) |
|---|---|---|---|---|
| Normal Control | 241.10 ± 0.53 | 92.90 ± 0.67 | 51.05 ± 0.53 | 7.51 ± 0.56 |
| Diabetic Control | 20.21 ± 0.15c | 34.80 ± 0.11c | 21.48 ± 1.34b | 5.85 ± 2.56d |
| Diabetic+5 mg/kg Gliben. | 220.71 ± 0.03b | 80.65 ± 0.84b | 52.69 ± 2.51a | 7.89 ± 2.32a |
| Diabetic+50 mg/kg FPEAP | 251.04 ± 0.07a | 87.40 ± 2.57b | 53.41 ± 0.87a | 8.59 ± 1.08b |
| Diabetic+100 mg/kg FPEAP | 238.85 ± 0.95a | 89.50 ± 0.05a | 53.93 ± 0.02a | 7.61 ± 0.01a |
| Diabetic+50 mg/kg BPEAP | 236.43 ± 1.55a | 81.10 ± 0.59b | 51.91 ± 0.56a | 8.18 ± 0.57b |
| Diabetic+100 mg/kg BPEAP | 227.00 ± 0.14b | 81.40 ± 0.60b | 53.00 ± 0.41a | 7.13 ± .007c |
Values represent mean ± SEM of six determinations (n = 6). Different superscripts indicate levels of significant difference down the column at p < 0.05. Note: T. Protein, total protein; Gliben., glibenclamide. Key: FPEAP, free phenolic extract of A. paniculata; BPEAP, bound phenolic extract of A. paniculata