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. 2021 Jan 28;11:2498. doi: 10.1038/s41598-021-82083-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Photomicrograph of the pulmonary sections of the different groups immunostained with C-KIT antibody. (A) The lung of G1 and (B) lung of G2 showing scarcely expression of C-KIT antibody within the pulmonary tissues. (C) Lung of G3 showing numerous C-KIT positive mast cells (arrows). (D) Lung of G4 showing decrease of C-KIT positive mast cells. (E) Lung of G5 showing marked decrease C-KIT positive mast cells, bar = 50 µm. (F) Quantitative score of the number of C-KIT positive mast cells. ¥ indicates significance in comparing with G1 (P < 0.001), * indicates significance in comparison with G3 (P < 0.001) and # indicates significance in comparison with G4 (P < 0.05).