Table 4.
Effect of thymoquinone supplementation and/or malathion inhalation on serum biochemistry of rats.
| Groups Parameters |
G1 | G2 | G3 | G4 | G5 |
|---|---|---|---|---|---|
| IgE (ng/ml) | 30.75 ± 7.59 cd | 28.13 ± 6.83d | 98.63 ± 9.61a | 56.38 ± 7.09b | 45.38 ± 7.42c |
| AST (U/L) | 56.48 ± 1.49c | 56.54 ± 2.25c | 113.65 ± 3.08a | 65.98 ± 4.55b | 48.40 ± 2.26c |
| ALT (U/L) | 39.12 ± 1.97c | 31.28 ± 1.89c | 85.22 ± 4.33a | 55.58 ± 3.39b | 39.35 ± 1.76c |
| ALP (U/L) | 147.80 ± 6.39 cd | 143.20 ± 7.21d | 232.00 ± 6.32a | 186.60 ± 4.68b | 164.80 ± 5.79c |
| Urea (mg/dl) | 25.99 ± 2.04d | 29.93 ± 1.68 cd | 59.08 ± 3.95a | 44.60 ± 2.81b | 34.89 ± 1.65c |
| Creatinine (mg/dl) | 0.93 ± 0.04c | 0.94 ± 0.06c | 1.66 ± 0.09a | 1.31 ± 0.03b | 1.17 ± 0.05b |
Values are expressed as mean ± standard errors. Means in the same row (a-b) with different subscript letters significantly differ at (p ≤ 0.05).
AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphatase.
G1 = control group, G2 = thymoquinone group (50 mg/kg body weight), G3 = malathion group G4 = malathion inhalation + thymoquinone 25 mg/kg body weight, and G5 = malathion inhalation + thymoquinone 50 mg/kg body weight.