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. 2021 Jan 28;11:2416. doi: 10.1038/s41598-021-81962-6

Figure 1.

Figure 1

The basic characteristics of TMGN with all six types of regulatory pairs (miRNA–gene, miRNA–TF, TF–miRNA, TF–gene, gene–gene and miRNA–miRNA). (A) A global of the network of TMGN. TFs, miRNAs and genes are colored green, orange and blue, respectively. (BE) The basic features of the network include degrees, clustering coefficients, topological coefficients and neighborhood connectivity of the network. (F) A sub-network with MYC as the central node. (G) A sub-network with ESR1 as the central node. TMGN: TF–miRNA–gene network; TF: transcription factor.