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. 2021 Jan 28;11:2416. doi: 10.1038/s41598-021-81962-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Gene Ontology and KEGG pathway analysis using genes and targets of miRNAs in CFMSN. (A) The top 10 pathways enriched by genes (left) and target genes of miRNAs (right). Pathways colored in red are common ones in both left and right. (B) The top 10 GO terms enriched by genes (left) and target genes of miRNAs (right). GO terms colored in red are common ones in both left and right. (C) A part of PI3K-Akt signaling pathway. (D) A part of Hepatitis B pathway. Genes with a yellow background is the risk genes from CFMSN. GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; CFMSN: 3/4/5-node composite FFL motif-specific sub-network.