Table 1.
Top 40 enriched genes per cluster ranked by fold change.
| Cycling progenitors | OPCs | Oligodendrocytes | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| CyP1 | CyP2 | CyP3 | OPC1 | OPC2a | OPC3 | OPC4 | OPC5 | OL1 | OL2 | AS1 | Peri |
| ASPM | HIST1H4C | PCLAF | RTN1 | HMP19 | IFI6 | TRIO | PLP1 | BCAS1 | MBP | GFAP | COL3A1 |
| CENPF | PCLAF | CLSPN | CRABP1 | FABP7 | H19 | HES1 | BCAS1 | MIR219A2 | PLP1 | CLU | LGALS1 |
| UBE2C | TOP2A | GINS2 | STMN2 | HIP1 | ISG15 | FGF12 | IFI6 | SIRT2 | CNP | AQP4 | COL1A1 |
| PTTG1 | HMGB2 | TYMS | ELAVL4 | NRXN1 | IGFBP5 | PHLDA1 | SIRT2 | KIF21A | RP11-89N17 | SPARCL1 | TAGLN |
| TOP2A | NUSAP1 | ORC6 | NNAT | STMN4 | B2M | HEY1 | ARHGAP5 | PLP1 | CLDN11 | ID3 | ELN |
| CCNB1 | MKI67 | CENPF | SOX4 | SCG3 | HLA-B | SOX6 | FAM13C | WASF1 | PTGDS | AGT | SPARC |
| CENPE | TUBA1B | HMGN2 | DCX | KCND2 | HLA-A | ARL4A | SLC44A1 | GPC3 | UGT8 | S100A10 | ACTA2 |
| NUF2 | CDK1 | SMC2 | SOX11 | NKAIN4 | HS3ST1 | ZFP36L2 | RP11-89N17 | PRDX1 | BCAS1 | CD99 | COL1A2 |
| HMGB2 | SMC4 | DUT | MIAT | OLIG1 | HLA-C | EGR1 | PRDX1 | UGT8 | KCTD12 | EDNRB | FBLN1 |
| NUSAP1 | PCNA | MCM7 | NREP | CCND2 | CD9 | RPS2P5 | WASF1 | SLC44A1 | MIR219A2 | NMB | BGN |
| TPX2 | RRM2 | TMSB15A | ETV1 | CALM1 | FOS | MAP2 | CENPJ | FAM13C | SEMA4D | MGST1 | MGP |
| MKI67 | HIST1H1D | MCM4 | HMP19 | C1orf61 | WWTR1 | RPL39 | FERMT1 | CNP | RGS16 | AHCYL1 | CALD1 |
| CKS2 | TPX2 | MAD2L1 | PEG10 | RAB31 | IFI16 | KHDRBS3 | FYN | EPB41L2 | SIRT2 | TGFB2 | SERPINH1 |
| PRC1 | HMGN2 | H2AFZ | NRXN1 | REV3L | SERPINE2 | RP4-765C7 | CNP | RAB33A | NFASC | CRYAB | TPM4 |
| KPNA2 | CENPF | TUBA1B | TAGLN3 | ID2 | TRIB2 | NKX2-2 | MBP | SGK1 | APLP1 | VIM | COL4A1 |
| SGO2 | SMC2 | RPA2 | FTX | PTPRZ1 | PMP2 | PLPPR1 | RNF13 | CADM2 | HMGCS1 | HSPB8 | S100A11 |
| NEK2 | BIRC5 | TUBB | CD24 | DBI | RBP1 | RPL13P12 | KIF21A | SMOC1 | CDK18 | EZR | TMSB4X |
| KIF14 | ESCO2 | PCNA | TERF2IP | RACK1 | BAALC | LIMA1 | CADM2 | ARHGAP5 | SLC44A1 | SPARC | GPC3 |
| BIRC5 | TYMS | RANBP1 | PIK3R1 | CNTN1 | HES5 | RND2 | FERMT1 | DLG1 | DTNA | DCN | |
| SMC4 | CENPU | NASP | CEP170 | NUPL2 | GABPB1-AS1 | TNR | DYNLL1 | CHN2 | FABP5 | ITGB1 | |
| AURKA | MAD2L1 | TOP2A | NFIB | SAT1 | MTATP6P1 | ATCAY | NFASC | FRMD4A | CA2 | CRABP2 | |
| ARL6IP1 | PRC1 | SNRPB | KDM5B | PLLP | HIST3H2A | UGT8 | FYN | MOG | ID1 | COL4A2 | |
| CDK1 | KNL1 | ARL6IP1 | HES6 | WSCD1 | RPL18A | MIR219A2 | GALNT13 | KIF21A | ID2 | OGN | |
| DLGAP5 | ATAD2 | SUPT16H | FNBP1L | C1orf21 | RPL36A | MOG | TMEM206 | ARHGAP5 | ANOS1 | FN1 | |
| MAD2L1 | ZWINT | HMGB1 | CRMP1 | CARS | EPN2 | GNB4 | CENPJ | CENPJ | PEA15 | ASPN | |
| FAM64A | DUT | RRM1 | TCF12 | CCND1 | TAOK3 | MYO5A | GPR17 | RAB33A | F3 | MYL9 | |
| CDC20 | H2AFZ | SRSF2 | DLL3 | FABP7 | COL11A1 | EPB41L2 | SEMA6D | TNR | DCLK1 | IGFBP7 | |
| GTSE1 | HIST1H1E | NUCKS1 | PKIA | MTSS1 | CCND1 | SMOC1 | FRMD4B | ENPP6 | CNN3 | SELENOM | |
| CCNB2 | UBE2C | SMC3 | TTC3 | DBI | GAS5 | SLC25A5 | HIPK2 | TM7SF3 | PSRC1 | TMSB10 | |
| CDKN3 | NDC80 | CKS1B | STMN4 | NDFIP1 | STMN2 | MOB3B | SLC25A5 | RND2 | ATP1B2 | PCOLCE | |
| CKAP2 | TUBB | GNG4 | MAP1B | GPR37L1 | ETV1 | CRB1 | ATCAY | CTD-2636A23 | CST3 | LUM | |
| KNL1 | MCM4 | SMC4 | FAM110B | ATP1B2 | TMEFF2 | HIPK2 | E2F3 | FAM13C | ID4 | COL6A3 | |
| CCNA2 | DHFR | AP2S1 | STMN1 | MALSU1 | GRIA2 | ERBB3 | SGCD | SGCD | TNC | PALLD | |
| KIF4A | KIF15 | CACYBP | ZNF292 | HMP19 | RP11-343H5 | MPZL1 | TNR | PRDX1 | B2M | LAPTM4A | |
| CKS1B | CLSPN | HMGB3 | SLC38A1 | RAB31 | RPSAP58 | PKP4 | APOD | GOLIM4 | CCDC80 | SSR2 | |
| HMGB3 | ANP32E | BZW2 | TCF4 | CD59 | CA10 | NFASC | SOX10 | TRIM2 | IGFBP7 | ACTN1 | |
| ANP32E | MIS18BP1 | PA2G4 | MAP2 | HIP1 | AC007969 | GPR17 | TCF7L2 | ARHGAP5-AS1 | RGMA | WFDC1 | |
| TUBB4B | NUF2 | NOP56 | HDAC2 | PHLDA1 | RPS29 | RAB33A | ENPP6 | MAG | HOPX | AKAP12 | |
| KIF20B | TMSB15A | EXOSC8 | MLLT11 | TRIM9 | TRAF4 | CHN2 | SOX2-OT | FYN | PON2 | TPM2 | |
| NDC80 | PTTG1 | HNRNPD | KIFAP3 | RGS16 | DANCR | TNS3 | GRIA2 | FBXO32 | SPON1 | CDH11 | |
The entire list of genes can be found in Supplementary Data 1.
OPC oligodendrocyte progenitor cells, AS astrocytes, Peri pericytes.
aOnly 19 enriched genes were identified for OPC2.