Fig. 3.

TAP1 inhibits PCa growth in vivo. (A) 1 × 10⁶ ALDH⁺CD44⁺CXCR4⁺CD24⁺ cells were injected subcutaneously into the NOD-SCID mice, n = 12. After 7 days of tumor cell implantation, mice were randomly divided into two groups (n = 6 per group) and treated with 10 μL (20 μM) peptide TAP1 or 10 μL (20 μM) control peptide every other day by intratumoral injection. Tumor vol`ume was measured every week. Volume = (width)[2] × length/2. (B) At 28 days of tumor cell implantation, tumors were harvested, photographed, and weighed. Data are presented as the mean ± SD. *p < 0.05.