Fig. 6.

TAP1 shortens the length of telomere and targets HOXB9 and TGF-β2. (A) ALDH⁺CD44⁺CXCR4⁺CD24⁺ and ALDH⁻CD44⁻CXCR4⁻CD24⁻ cells were incubated in TAP1 (20 μM) for 72 h followed by flow-FISH analysis to determine telomere lengths. Representative images (left panel). Summary data (right panel). (B) ALDH⁺CD44⁺CXCR4⁺CD24⁺ were incubated with TAP1 (20 μM) or control peptide (20 μM) for 72 h. Western blot analysis of the protein expression. GAPDH is used as a loading control. Data are presented as the mean±SD. *p < 0.05.