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. 2021 Jan 26;6(8):2372–2389. doi: 10.1016/j.bioactmat.2021.01.017

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 9 — (A) Treatment schedule. (B) H&E staining and Safranin O/Fast green staining of the articular cartilage after 6 weeks treatment with different samples (scale bar: top and center, 450 μm; bottom, 150 μm). (C) Immunohistochemisy analysis of the articular cartilage after 6 weeks treatment with different samples (n = 5, scale bar: 45 μm). (D) The overall OARSI scores of the articular cartilage. (E) Relative expression of P65, MMP9 and LC3B for each group. ** indicate p < 0.01; *** indicate p < 0.001.