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. 2021 Jan 1;12(1):59–70. doi: 10.6004/jadpro.2021.12.1.5

Table 1. Summary of Efficacy: Controlling Plasma Uric Acid.

Rasburicase Rasburicase + allopurinol Allopurinol
Response rate (% of patients with plasma uric acid levels ≤ 7.5 mg/dL between days 3 and 7) 87% 78% 66%
Plasma uric acid response rate: patients at high risk for TLS 89% 68%
Plasma uric acid response rate: patients with baseline hyperuricemia 90% 53%
Time to plasma uric acid control for hyperuricemic patients 4 hr 4 hr 27 hr

Note. Information from Cortes et al. (2010); Dinnel et al. (2015); Maloney & Denno (2011); Sanofi-aventis US, LLC. (2019).