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. 2021 Jan 28;11:2420. doi: 10.1038/s41598-021-81802-7

Table 4.

Left/right hippocampus and grouped hippocampal subfield volumetric differences.

High-risk preterm
n = 16
Mean ± SD
Low-risk preterm
n = 20
Mean ± SD
Full-term
n = 22
Mean ± SD
F-Snedecor Statistic (p) ηp2
Hippocampus (mm3) (covariate according to eTIV, age and presence of shunt valve)
Left Hippocampus 2,971.73 ± 579.95 3,459.27 ± 390.23 3,399.56 ± 271.96 13.00 (< .001)* .56
Right Hippocampus 2,974.33 ± 424.70 3,352.35 ± 382.10 3,402.27 ± 288.50 26.53 (< .001)* .72
Grouped hippocampal subfields (mm3) (covariate according to eTIV, age and presence of shunt valve)
Left Subiculum 253.85 ± 62.63 301.99 ± 25.09 325.08 ± 31.07 10.73 (< .001)* .51
Right Subiculum 241.49 ± 42.45 280.87 ± 29.85 299.92 ± 30.72 14.82 (< .001)* .59
Left CA-field 1582.24 ± 322.00 1853.45 ± 231.12 1803.92 ± 156.22 12.74 (< .001)* .55
Right CA-field 1606.23 ± 231.57 1812.39 ± 229.66 1841.89 ± 169.12 21.49 (< .001)* .67
Left Dentate Gyrus 498.84 ± 86.81 567.66 ± 86.26 547.14 ± 53.92 13.38 (< .001)** .56
Right Dentate Gyrus 509.74 ± 77.95 545.44 ± 77.38 545.16 ± 69.63 15.27 (< .001)* .60

SD: standard deviation; mm3: cubic millimeter; and ηp2: partial eta squared.

*Statistically significant differences between High-risk preterm < Full-term and High-risk preterm < Low-risk preterm.

**Statistically significant differences between High-risk preterm < Low-risk preterm. The global bilateral hippocampal volumes and grouped hippocampal subfield volumes shown in bold are those that remained significant after Bonferroni correction was applied for multiple comparisons (p = .006).