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. 2021 Jan 15;8:575097. doi: 10.3389/fped.2020.575097

Table 1.

Demographic data of the patients.

Variables (n = 144) AKI NAKI Total
(n = 460) (n = 604)
Age (h) N 144 460 604
Median (range) 2.4 (0.5, 70.3) 2.3 (0.3, 72) 2.3 (0.3, 72)
Gestational age (week) N 144 457 601
Median (range) 29.1 (25.1, 36.3) 30.9 (24.9, 40.3) 30.3 (24.9, 40.3)
Birth weight (g) N 144 460 604
Median (range) 1,240 (600, 1,490) 1,320 (550, 1,495) 1,300 (550, 1,495)
Apgar 5 N 137 437 574
Median (range) 8 (2, 10) 9 (1, 10) 9 (1, 10)
Maternal age (year) <35 years 115 (79.9%) 385 (84.1%) 500 (83.1%)
≥35 years 29 (20.1%) 73 (15.9%) 102 (16.9%)
Sex of infant Female 61 (42.4%) 238 (51.7%) 299 (49.5%)
Male 83 (57.7%) 222 (48.3%) 305 (50.5%)
Type of delivery Normal delivery 95 (66.0%) 220 (47.9%) 315 (52.2%)
Cesarean section 49 (34.0%) 239 (52.1%) 288 (47.8%)
RBC (×1012/L) N 143 459 602
Mean (SD) 4.1 (0.7) 4.4 (0.7) 4.4 (0.7)
Hb (g/L) N 143 459 602
Median (range) 330 (284.5, 368.5) 336 (283, 411) 334.5 (283, 411)
UN (mmol/L) N 144 458 602
Median (range) 3.9 (1, 12.3) 3.7 (1.1, 19.6) 3.7 (1, 19.6)
CysC (mg/L) N 35 76 111
Mean (SD) 2 (0.4) 1.9 (0.3) 1.9 (0.3)
P (mmol/L) N 144 459 603
Median (range) 2.2 (1, 5.4) 2.1 (0.8, 4.3) 2.1 (0.8, 5.4)
Ca (mmol/L) N 144 459 603
Median (range) 1.9 (0.9, 2.5) 2.1 (1, 2.8) 2 (0.9, 2.8)
Respiratory failure 22 (15.5%) 165 (36.7%) 187 (31.6%)
+ 120 (84.5%) 285 (63.3%) 405 (68.4%)
Sepsis 54 (38.0%) 235 (52.2%) 289 (48.8%)
+− 20 (14.1%) 63 (14%) 83 (14.0%)
+ 68 (47.9%) 152 (33.8%) 220 (37.2%)
Brain injury 110 (77.5%) 385 (85.6%) 495 (83.6%)
+ 32 (22.6%) 65 (14.4%) 97 (16.4%)
Pulmonary hypertension 67 (47.2%) 336 (74.7%) 403 (68.1%)
+ 75 (52.8%) 114 (25.3%) 189 (31.9%)
PDA 33 (23.2%) 213 (47.3%) 246 (41.6%)
+ 109 (76.8%) 237 (52.7%) 346 (58.5%)
Myocardial injury 46 (32.4%) 217 (48.2%) 263 (44.4%)
+ 96 (67.6%) 233 (51.8%) 329 (55.6%)
Neonatal hyperbilirubinemia 31 (21.8%) 137 (30.4%) 168 (28.4%)
+ 111 (78.2%) 313 (69.6%) 424 (71.6%)
NEC 111 (78.2%) 369 (82.0%) 480 (81.1%)
+− 19 (13.4%) 51 (11.3%) 70 (11.8%)
+ 12 (8.5%) 30 (6.7%) 42 (7.1%)
Neonatal asphyxia 77 (53.47%) 282 (61.3%) 359 (59.44%)
+ 65 (45.14%) 168 (36.52%) 233 (38.58%)

+, yes; –, no; +−, suspected.

AKI, acute kidney injury; NAKI, non-acute kidney injury; N, number; Apgar 5, 5-min Apgar score; RBC, red blood cell count within 3 days of birth; Hb, hemoglobin concentration within 3 days of birth; UN, urea nitrogen within 3 days of birth; CysC, serum cystatin C within 3 days of birth; P, phosphorus concentration within 3 days of birth; Ca, calcium concentration within 3 days of birth; PDA, patent ductus arteriosus; NEC, necrotizing enterocolitis.