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. 2021 Jan 15;11:602908. doi: 10.3389/fgene.2020.602908

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Copyright © 2021 Liu, Zhang, Chen, Wang, Chen, Liu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of advanced plaque-related modules in dataset GSE43292 and GSE28829. (A,B) Module-trait associations. Branches of the dendrogram group together module eigengene values that are positively correlated. Each row and column in the lower left heatmap correspond to one module eigengene (labeled by color) or advanced plaques, in which blue color represents negative correlation, while red represents positive correlation. Each row in the right heatmap corresponds to a module eigengene, column to the advanced plaques. Each cell contains the corresponding correlation and p-value. The table is color-coded by correlation according to the color legend. (C,D) The PCA for genes within advanced plaque-related modules in response to advanced plaques.