Table 4.

KRAS borderline samples with one or two positive droplets in cfDNA.

Patient ID	Diagnosis- Sensitizing MUT EGFR	Progression Disease - MUT EGFR in liquid biopsy	KRAS n° of positive droplets (MAFA)	Age at diagnosis (years)	Smoking	PS	Stage at Diagnosis	PFS (months)	TTF (months)	OS (months)
16	L858R	no mutation	1 (0.12%)	72	no	1	IV	11	21	21
20	ex19 del	no mutation	2 (0.32%)	73	no	0	IV	28	33	39
54	ex19 del	no mutation	1 (0.10%)	85	\	1	IVb	48	60	69
56	L858R	no mutation	1 (0.10%)	49	no	0	IVb	3	9	9
57	G719	no mutation	1 (0.30%)	63	ex	0	Ib	10	19	53
78	ex19 del	no mutation	1 (0.19%)	71	\	0	IVa	31	46	48
81	ex19 del	no mutation	1 (0.22%)	72	no	0	IVa	13	35	49
92	ex19 del	no mutation	1 (0.30%)	75	ex	0	IV	40	41	51
3	ex19 del	ex19 del	1 (0.24%)	80	no	1	IV	32	40	46
9	ex19 del	ex19 del	2 (0.06%)	67	ex	2	IV	5	8	10
23	ex19 del	ex19 del	1 (0.25%)	60	no	0	IV	8	11	23
29	ex19 del	ex19 del	1 (0.07%)	63	ex	0	IV	9	14	19
33	ex19 del	ex19 del	1 (0.31%)	56	no	1	IV	4	4	4
45	ex19 del	ex19 del	1 (0.07%)	64	no	1	IV	15	17	21
52	ex19 del	ex19 del	1 (0.11%)	67	no	1	IVb	5	5	11
91	ex19 del	ex19 del	1 (0.15%)	55	\	0	Ia	16	46	56
102	ex19 del	ex19 del	1 (0.18%)	68	no	1	IV	9	10	22
48	L858R	L858R	1 (0.29%)	79	no	1	IV	17	25	26
76	L858R	L858R	2 (0.07%)	54	no	1	IIIb	18	19	30
44	L858R	L858R - S768I	1 (0.016%)	44	no	0	Ib	7	9	17
19	ex19 del	ex19 del - T790M	1 (0.03%)	68	yes	0	Iib	10	10	42
27	ex19 del	ex19 del - T790M	1 (0.12%)	37	no	0	IV	10	35	90
30	ex19 del	ex19 del - T790M	1 (0.22%)	51	no		IV	6	23	35
41	ex19 del	ex19 del - T790M	2 (0.24%)	64	ex	0	IV	15	2	44
43	ex19 del	ex19 del - T790M	1 (0.07%)	66	no	1	IV	8	12	30
49	ex19 del	ex19 del - T790M	1 (0.21%)	82	ex	0	IV	22	28	69
60	ex19 del	ex19 del - T790M	1 (0.20%)	60	no	1	IIIa	6	26	41
36	L858R	L858R - T790M	1 (0.16%)	71	no	1	IV	6	7	16