Table 3.

Brain regions with significant group effects in the nodal clustering coefficient between the CP1, CP2, and HC groups (post hoc t-test; FDR-corrected P < 0.05).

Brain regions		Nodal clustering coefficient		t	P
CP1 < HC	Left middle frontal gyrus	0.12 ± 0.020	0.15 ± 0.015	−4.50	0.00012
	Right inferior frontal gyrus (triangular part)	0.12 ± 0.012	0.15 ± 0.018	−5.62	0.000006
	Right posterior cingulate gyrus	0.18 ± 0.024	0.25 ± 0.060	−4.07	0.00037
	Left calcarine fissure	0.10 ± 0.016	0.13 ± 0.011	−5.73	0.000004
	Left cuneus	0.12 ± 0.020	0.15 ± 0.014	−4.26	0.00022
	Left inferior parietal gyri	0.12 ± 0.013	0.15 ± 0.022	−4.52	0.00011
	Left angular gyrus	0.14 ± 0.015	0.17 ± 0.021	−5.24	0.000016
	Left precuneus	0.08 ± 0.010	0.10 ± 0.012	−5.13	0.000022
	Right precuneus	0.07 ± 0.011	0.09 ± 0.010	−4.47	0.00013
	Right pallidum	0.25 ± 0.076	0.41 ± 0.096	−4.99	0.000032
CP2 < HC	Left middle frontal gyrus	0.12 ± 0.011	0.15 ± 0.015	−5.58	0.000006
	Right insula	0.08 ± 0.011	0.11 ± 0.021	−4.29	0.0002
	Right hippocampus	0.10 ± 0.016	0.13 ± 0.021	−4.18	0.00027
	Left calcarine fissure	0.10 ± 0.014	0.13 ± 0.011	−5.70	0.000005
	Left cuneus	0.12 ± 0.020	0.15 ± 0.014	−4.73	0.000064
	Left lingual gyrus	0.09 ± 0.018	0.12 ± 0.018	−4.02	0.00042
	Left postcentral gyrus	0.11 ± 0.013	0.13 ± 0.016	−4.61	0.000086
	Left angular gyrus	0.14 ± 0.024	0.17 ± 0.021	−4.14	0.00031
	Left precuneus	0.08 ± 0.011	0.10 ± 0.012	−5.21	0.000017
	Right precuneus	0.07 ± 0.011	0.09 ± 0.010	−4.89	0.000041
	Left paracentral lobule	0.12 ± 0.014	0.17 ± 0.028	−5.21	0.000017
	Right paracentral lobule	0.16 ± 0.020	0.21 ± 0.030	−5.03	0.000028
CP1 < CP2	Right inferior frontal gyrus (triangular part)	0.25 ± 0.076	0.36 ± 0.057	−3.96	0.00052
	Right pallidum	0.12 ± 0.012	0.15 ± 0.023	−4.39	0.00017

CP1, children with bilateral spastic cerebral palsy before treatment; CP2, children with bilateral spastic cerebral palsy following treatment; HC, health children. FDR-corrected P < 0.05 indicated statistically significant differences between groups.