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. 2021 Jan 15;8:617548. doi: 10.3389/fped.2020.617548

Table 5.

Brain regions with significant group effects in the nodal path length between the CP1, CP2, and HC groups (post hoc t-test; FDR-corrected P < 0.05).

Brain regions Nodal clustering coefficient t P
CP1>HC Right median cingulate gyri 9.34 ± 1.27 7.56 ± 0.95 4.31 0.0002
Right posterior cingulate gyrus 10.25 ± 1.47 8.41 ± 0.81 4.20 0.00026
Right hippocampus 11.01 ± 1.33 9.02 ± 1.24 4.19 0.00027
Left lingual gyrus 12.33 ± 1.20 10.36 ± 1.05 4.68 0.000071
Left superior occipital gyrus 13.98 ± 1.49 11.96 ± 0.89 4.48 0.00012
Left middle occipital gyrus 12.60 ± 1.43 10.47 ± 1.14 4.46 0.00013
Left fusiform gyrus 13.91 ± 1.80 11.82 ± 0.94 3.94 0.00051
Left angular gyrus 14.64 ± 1.89 11.92 ± 1.69 4.09 0.00035
Left precuneus 10.23 ± 1.51 8.25 ± 0.95 4.26 0.00022
Right putamen 12.12 ± 1.18 10.09 ± 1.16 4.70 0.000069
Right thalamus 11.13 ± 1.68 8.69 ± 0.84 4.99 0.000031
CP2>HC Left precental gyrus 10.21 ± 1.02 8.76 ± 0.72 4.43 0.00014
Left inferior frontal gyrus (opercular part) 12.81 ± 1.17 11.24 ± 1.11 3.70 0.00098
Right supplementary motor area 11.39 ± 0.74 10.12 ± 0.92 4.10 0.00034
Left postcentral gyrus 10.26 ± 0.77 9.10 ± 0.78 4.04 0.0004
Left precuneus 9.77 ± 0.91 8.25 ± 0.95 4.41 0.00015
Left paracentral lobule 11.12 ± 0.84 9.65 ± 0.82 4.74 0.000061
Right paracentral lobule 12.46 ± 1.10 10.70 ± 0.82 4.89 0.00004
CP1>CP2 Right putamen 12.12 ± 1.18 10.61 ± 0.75 4.05 0.00041
Right thalamus 11.13 ± 1.68 9.21 ± 0.65 3.99 0.00048

CP1, children with bilateral spastic cerebral palsy before treatment; CP2, children with bilateral spastic cerebral palsy following treatment; HC, health children. FDR-corrected P < 0.05 indicated statistically significant differences between groups.