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. 2020 Dec 26;58(2):123–131. doi: 10.1177/0004563220981106

Table 1.

Stability of COVID-19 antibodies under various conditions of temperature and humidity.


Length of storage (days)
Storage conditions 0 1 3 7 14 21 28
–20°C, low humidity 100 93 100 103 101 97 97
–20°C, ambient humidity 100 107 109 99 109 97 90
+4°C, low humidity 100 99 102 104 105 92 102
+4°C, ambient humidity 100 105 98 104 97 92 92
RT, low humidity 100 107 103 103 99 96 102
RT, ambient humidity 100 99 104 103 102 97 93
RT, high humidity 100 97 102 102 91 92 94
40°C, low humidity 100 108 101 96 95 90 91
40°C, ambient humidity 100 107 97 96 94 90 97
40°C, high humidity 100 81 65 57 45 29 27

DBS specimens were stored at the various temperatures and conditions. At the various time intervals, samples were removed and stored desiccated in sealed foil bags at –20°C prior to analysis in duplicate at the end of the study. Results shown are % residual OD, using DBS specimens that were stored desiccated at –20°C, during the study period as the control (i.e. 100%) and analysed alongside those specimens subjected to the various heat and humidity conditions. The mean (SD) OD for the 100% control was 1.52 (0.14).