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. 2021 Jan 27;28:1–9. doi: 10.1016/j.jot.2020.11.009

Table 1.

Groups with different interventions in rabbits radial defect model and Rhesus monkey calvarial defect model.

Animal model Groups Implant side (left) Control side (right)
New Zealand rabbit model SIM50mg simvastatin 50 ​mg ​+ ​PLA 250 ​mg+2 ​ml acetone PLA 250 ​mg+2 ​ml acetone
SIM100mg simvastatin 100 ​mg ​+ ​PLA 250 ​mg+2 ​ml acetone PLA 250 ​mg+2 ​ml acetone
SIM200mg simvastatin 200 ​mg ​+ ​PLA 250 ​mg+2 ​ml acetone PLA 250 ​mg+2 ​ml acetone
Autograft autogenous bone void
Rhesus monkey model SIM50mg simvastatin 50 ​mg ​+ ​thrombin 0.4 ​ml ​+ ​fibrin sealant 0.4 ​ml thrombin+0.4 ​ml fibrin sealant