Table 1.
Groups with different interventions in rabbits radial defect model and Rhesus monkey calvarial defect model.
Animal model | Groups | Implant side (left) | Control side (right) |
---|---|---|---|
New Zealand rabbit model | SIM50mg | simvastatin 50 mg + PLA 250 mg+2 ml acetone | PLA 250 mg+2 ml acetone |
SIM100mg | simvastatin 100 mg + PLA 250 mg+2 ml acetone | PLA 250 mg+2 ml acetone | |
SIM200mg | simvastatin 200 mg + PLA 250 mg+2 ml acetone | PLA 250 mg+2 ml acetone | |
Autograft | autogenous bone | void | |
Rhesus monkey model | SIM50mg | simvastatin 50 mg + thrombin 0.4 ml + fibrin sealant | 0.4 ml thrombin+0.4 ml fibrin sealant |