Table 2.
GO and KEGG Pathway Enrichment Analyses of DEGs in Rhabdomyosarcoma Samples.
Term | Description | Count in gene set | P-value |
---|---|---|---|
GO:0007049 | Cell cycle | 52 | 9.31E-09 |
GO:0006936 | Muscle contraction | 44 | 1.79E-31 |
GO:0003012 | Muscle system process | 44 | 1.3E-29 |
GO:0007010 | Cytoskeleton organization | 43 | 2.01E-12 |
GO:0007517 | Muscle organ development | 36 | 9.77E-18 |
GO:0043232 | Intracellular non-membrane-bounded organelle | 134 | 1.09E-14 |
GO:0043228 | Non-membrane-bounded organelle | 134 | 1.09E-14 |
GO:0005856 | Cytoskeleton | 104 | 2.03E-22 |
GO:0044430 | Cytoskeletal part | 79 | 4.19E-19 |
GO:0005739 | Mitochondrion | 55 | 1.32E-05 |
GO:0000166 | Nucleotide binding | 77 | 0.04579 |
GO:0008092 | Cytoskeletal protein binding | 69 | 4.11E-28 |
GO:0017076 | Purine nucleotide binding | 69 | 0.02485 |
GO:0032555 | Purine ribonucleotide binding | 63 | 0.07086 |
GO:0032553 | Ribonucleotide binding | 63 | 0.07086 |
hsa04260 | Cardiac muscle contraction | 19 | 3.74E-11 |
hsa05414 | Dilated cardiomyopathy | 17 | 3.82E-08 |
hsa05410 | Hypertrophic cardiomyopathy | 16 | 8.51-08 |
hsa05010 | Alzheimer’s disease | 14 | 0.00279 |
hsa04530 | Tight junction | 13 | 0.00152 |
GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DEGs, differentially expressed genes