Table 1. Clinical and pathological characteristics stratified by CD3+ T cell count, CD4+ T cell count and CD4/CD8 ratio in patients with ccRCC.

Variables	CD3+ T cell count				CD4+ T cell count				CD8+ T cell count				CD4+/CD8+ ratio
	Low (<770)	High (>770)	P		Low (<500)	High (>500)	P		Low (<238)	High (>238)	P		Low (<1.0)	High (>1.0)	P
Age (y)			0.614				0.994				0.630				0.020
<65	16	47			26	37			13	50			8	55
>65	6	11			7	10			2	15			7	10
Sex			0.612				0.624				0.392				0.034
Male	15	36			20	31			11	40			6	45
Female	7	22			13	16			4	25			9	20
Hypertension			0.787				0.921				0.025				0.912
Yes	8	23			13	18			2	29			6	25
No	14	35			20	29			13	36			9	40
Diabetes mellitus			0.984				1.000				0.865				0.865
Yes	3	6			4	5			1	8			1	8
No	19	52			29	42			14	57			14	57
Location			0.291				0.698				0.014				0.031
Left	12	24			14	22			11	25			6	34
Right	10	34			19	25			4	40			9	31
Surgical approach			0.075				0.004				0.026				0.519
NSS	14	24			22	16			11	27			6	32
RN	8	34			11	31			4	38			9	33
BMI (kg/m2)			0.358				0.578				0.005				1.000
<25	15	33			21	27			12	36			9	39
>25	7	25			12	20			3	29			6	26
NLR			<0.001				<0.001				0.166				0.166
<3	8	49			16	41			8	49			8	49
>3	14	9			17	6			7	16			7	16
PLR			0.002				0.001				0.007				0.694
<132	5	36			9	32			3	38			7	34
>132	17	22			24	15			12	27			8	31
CD3+ T cell (cells/μL)			-				<0.001				<0.001				0.128
<770	22	0			22	0			14	8			7	15
>770	0	58			11	47			1	57			8	50
CD4+ T cell (cells/μL)			<0.001				–				<0.001				0.102
<500	22	11			33	0			14	19			9	24
>500	0	47			0	47			1	46			6	41
CD8+ T cell (cells/μL)			<0.001				<0.001				–				0.035
<238	14	1			14	1			15	0			1	14
>238	8	57			19	46			0	65			14	51
CD4+/CD8+			0.128				0.102				0.335				–
<1.0	7	8			9	6			1	14			15	0
>1.0	15	50			24	41			14	51			0	65
MAP score			0.201				0.882				0.519				0.099
0–2	9	33			17	25			9	33			5	37
3–5	13	25			16	22			6	32			10	28
RENAL score			0.006				0.403				0.039				0.702
4–6	2	24			9	17			1	25			6	20
7–12	20	34			24	30			14	40			9	45
Tumor size (cm)			0.001				0.063				0.002				0.452
<5	4	35			12	27			2	37			6	33
>5	18	23			21	20			13	28			9	32
T stage			0.081				0.464				0.509				0.925
T1-2	15	51			26	40			11	55			13	53
T3-4	7	7			7	7			4	10			2	12
Fuhrman grade			0.007				0.103				0.047				0.801
1–2	7	38			15	30			5	40			8	37
3–4	15	20			18	17			10	25			7	28

BMI, body mass index; MAP, Mayo adhesive probability; NLR, neutrophil to lymphocyte ratio; NSS, nephron sparing surgery; PLR, platelet to lymphocyte ratio; RN, radical nephrectomy.